IC-APP-IC-SICM

HIGHLIGHTS
Scanning Ion Conductance Microscopy (SICM)

Nanoscale resolution mapping of single cell
3D mapping of live cells imaging in physiological conditions without fixing
(Hopping Probe SICM, patented HPICM)
Dynamic morphological changes of cell surface observations
(Simultaneous fast hopping mode SICM and Fluorescence Confocal Microscopy (SICM-FCM))
Study of ion channels in live cells and submicrometric cellular structure
(SICM & Patch Clamping - High-resolution scanning patch-clamp system)
Local dosing using SICM
(by changing the voltage/pressure in the nanopipette)
Nanomechanical mapping of both molecules and living cells
(nanomechanical measurements can be obtained with or without applied pressure to the nanopipette)
Local Biosensing (3D pH mapping) and Nanoprobes (monitor oxygen consumption and reactive oxygen species (ROS)) of single cell within its environment
(label-free high-sensitivity pH detection via self-assembly zwitterion-like membrane at the tip of the pipette)